Medical applications of plasma-activated treatment equipment

• Categories:Industry News
• Author:plasma cleaning machine-surface treatment equipment-CRF plasma machine-Sing Fung Intelligent Manufacturing
• Origin:
• Time of issue:2020-11-06
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(Summary description)In some cases, surface modification and activation of cultured cells are necessary to improve cell adhesion and cell growth rate. Under special conditions, cell adhesion was a necessary condition to ensure cell proliferation, and the cell proliferation rate of the culture dish treated by plasma activation equipment was significantly higher than that of the untreated culture dish. The results show that the modification and activation of polyester, polyethylene and K resin by plasma can significantly improve their adhesion properties.   Compared with other materials, the surface friction coefficient of polymers such as silicone and polyurethane is higher. After plasma surface activation treatment, the instrument made of this material is coated with a layer of polymer with low friction coefficient to make its surface more lubricated. For example, after plasma surface activation, the adhesion of hydrogel coating on the surface of medical catheter can be improved, thus reducing the friction between the medical catheter and the blood vessel wall. Catheters for the urethral, respiratory, tracheal, and cardiovascular systems, or instruments for endoscopic/laparoscopic surgery, and ophthalmic materials, when in contact with body fluids, have a good hydrophilic properties, so that when body fluids come into contact with the surfaces of these smooth medical devices, they do not stick to their surfaces. Plasma ionized gases can reduce this friction coefficient on the surface. Small friction coefficient of medical devices, when inserted or removed from the patient's body, can reduce the mechanical damage to the patient's mucosa, reduce the patient's discomfort. Plasma technology in combination with other technologies, especially xylene polymer coating, has been successfully used in the manufacture of a variety of medical devices, such as ophthalmology and imaging surgery.   Film deposition method is used to deposit a barrier layer on the surface of plastic products to reduce the permeability of liquid such as alcohol to the surface of plastic products. For example, treating high-density polyethylene (HDPE) with plasma-activated equipment reduces the material's permeability to alcohol by a factor of 10. Due to the interaction between blood and certain chemical components in biological materials, blood clotting can be caused and human health is jeopardized. Therefore, implants made of biological materials such as silicone rubber, polyester, polytetrafluoroethylene, polyurethane and PVC can only stay in the blood for a short time. For example, dioctyl phthalates (DOP) and certain stabilizers in PVC blood bags are slowly released from the PVC base and react with the blood, causing blood to clot. After plasma treatment of PVC material, a cross-linked film is formed on the surface. The film is biocompatible, which can adjust the dispersion degree of the film within a small range and play a role in controlling the transmission of substances such as stabilizer.   Plasma-modified and activated membrane materials can improve the selectivity of diffused materials. Generally, it is necessary for membrane materials to have high permeability and high selectivity to permeable materials. By controlling the pore size and combining with chemical action or physical restriction, the membrane surface selectivity can be improved, which is beneficial to the application of biological separation process in hemodialysis and protein purification.   In general, diagnostic biosensors often require biological components such as enzymes or antibodies to be fixed to the surface of the sensor. Plasma grafting and surface functional activation treatment provide a convenient and effective method for establishing covalent bonding between biological components and substrates.